Targeting ofHelicobacter pyloriVacA to mitochondria
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چکیده
منابع مشابه
Bacterial proteins predisposed for targeting to mitochondria.
Mitochondria evolved from an endosymbiotic proteobacterium in a process that required the transfer of genes from the bacterium to the host cell nucleus, and the translocation of proteins thereby made in the host cell cytosol into the internal compartments of the organelle. According to current models for this evolution, two highly improbable events are required to occur simultaneously: creation...
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Correct targeting of nuclear-encoded, cytoplasmicallysynthesized proteins to mitochondria is one facet of a diverse pattern of intracellular traffic of nascent polypeptides that occurs within all eukaryotic cells. The complex internal organization of cells necessitates that organellar or secreted polypeptides, initially formed in the cytoplasm, must be delivered efficiently across one or more i...
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Immature erythroid cells have an exceptionally high capacity to synthesize haem that is, at least in part, the result of the unique control of iron metabolism in these cells. In erythroid cells the vast majority of Fe released from endosomes must cross both the outer and the inner mitochondrial membranes to reach ferrochelatase, which inserts Fe into protoporphyrin IX. Based on the fact that Fe...
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MITOCHONDRIA PRESENT TWO KEY ROLES ON CELLULAR FUNCTIONING: (i) cell metabolism, being the main cellular source of energy and (ii) modulation of cell death, by mitochondrial membrane permeabilization. Carbon monoxide (CO) is an endogenously produced gaseoustransmitter, which presents several biological functions and is involved in maintaining cell homeostasis and cytoprotection. Herein, mitocho...
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ژورنال
عنوان ژورنال: Gut Microbes
سال: 2010
ISSN: 1949-0976,1949-0984
DOI: 10.4161/gmic.1.6.13894